HDAC-IN-66
HDAC-IN-66 (compound 2F) is a selective HDAC inhibitor and Pomalidomide derivative that potently inhibits hematological tumor cells[1].
Product Specifications
CAS Number
3055552-04-7
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-66.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=CC=C1NC(C2=CC=C(CNC3=CC=CC(C(N4C5C(NC(CC5)=O)=O)=O)=C3C4=O)C=C2)=O
Molecular Formula
C27H23N5O5
Molecular Weight
497.50
References & Citations
[1]Chen D et al. Serendipitous discovery of Class I HDAC inhibitors from rational design of molecular glue degraders targeting HDAC. Eur J Med Chem. 2023 Nov 19;263:115926.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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