HDHODH-IN-14
HDHODH-IN-14 (compound 14) is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an IC50 of 0.469 μM[1].
Product Specifications
CAS Number
881826-17-1
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hdhodh-in-14.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(/N=C(NC/2=O)\SC2=C/C3=CC=CC4=C3C=CC=C4)C=CC=C1)O
Molecular Formula
C21H14N2O3S
Molecular Weight
374.41
References & Citations
[1]Xiaoli Ren, et al. Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking. Chem Biol Drug Des. 2023 Nov 5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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