NLRP3-IN-23
NLRP3-IN-23 (Compound 15C) is an inhibitor of heme-mediated induction of the NLRP3 inflammasome. NLRP3-IN-23 significantly inhibits heme-mediated induction of the NLRP3 inflammasome at a concentration of 0.1 μM[1].
Product Specifications
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-23.html
Solubility
10 mM in DMSO
Smiles
O=C(C=C1[Si](C)(CCCCCC)C)C([C@@H]2C=C(C)CC[C@H]2C(C)=C)=C(O)C1=O
Molecular Formula
C24H36O3Si
Molecular Weight
400.63
References & Citations
[1]Shete S S, et al. Sila-CBD Derivatives as Inhibitors of Heme-Induced NLRP3 Inflammasome: Application in Hemolytic Diseases[J]. ACS Medicinal Chemistry Letters, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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