MMP-9-IN-8
MMP-9-IN-8 (Compound 3) is an MMP-9 inhibitor with inhibitory activities of 42.16% and 58.28% at 10 μM and 50 μM concentrations, respectively. MMP-9-IN-8 has anti-cancer activity and can induce apoptosis in MCF-7 cells with an IC50 value of 23.42 μM[1].
Product Specifications
CAS Number
[2490543-89-8]
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mmp-9-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C(C(F)(F)F)=C1)F)NC2=NC(N3CCN(CC3)C)=C(C=CN4C)C4=N2
Molecular Formula
C20H21F4N7O
Molecular Weight
451.42
References & Citations
[1]Kilic-Kurt Z, et al. Effects of pyrrolopyrimidine derivatives on cancer cells cultured in vitro and potential mechanism. Naunyn Schmiedebergs Arch Pharmacol. 2023 Oct 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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