HCAIX-IN-19
HCAIX-IN-19 is a sulfonamides inhibitor against hCA IX with an inhibition constant (KI) of 6.2 nM and show good selectivity over hCA I (hCA I/ hCA IX = 117) [1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-19.html
Solubility
10 mM in DMSO
Smiles
O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(N(CC3=CC=C(C=CC=C4)C4=C3)CCC5=CC=C(S(=O)(N)=O)C=C5)=O)([H])N1
Molecular Formula
C29H34N4O4S2
Molecular Weight
566.73
References & Citations
[1]Begines P, et al. Design and synthesis of sulfonamides incorporating a biotin moiety: Carbonic anhydrase inhibitory effects, antiproliferative activity and molecular modeling studies [J]. Bioorganic & Medicinal Chemistry, 2023, 94: 117467.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA IX
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS728151-01 48 Well
Mouse Soluble Interleukin 2a receptor ELISA Kit
Sign In for Pricing
View Details MBS728151-02 96 Well
Mouse Soluble Interleukin 2a receptor ELISA Kit
Sign In for Pricing
View Details