FAAH-IN-8

FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 value of 6.7 nM and a Ki value of 5 nM. FAAH-IN-8 has high blood-brain permeability and a significant antioxidant profile with no neurotoxicity[1].

Product Specifications

CAS Number

[2867633-84-7]

UNSPSC

12352005

Target

FAAH

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/faah-in-8.html

Solubility

10 mM in DMSO

Smiles

O=C1N(CC=C)C2=C(C=CC=C2)/C1=N/C3=NC4=CC=CC=C4N3

Molecular Formula

C18H14N4O

Molecular Weight

302.33

References & Citations

[1]Shivani Jaiswal, et al. Lead optimization study on indoline-2,3-dione derivatives as potential fatty acid amide hydrolase inhibitors. J Biomol Struct Dyn. 2023, 41 19.