FAAH-IN-8
FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 value of 6.7 nM and a Ki value of 5 nM. FAAH-IN-8 has high blood-brain permeability and a significant antioxidant profile with no neurotoxicity[1].
Product Specifications
CAS Number
2867633-84-7
UNSPSC
12352005
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/faah-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C1N(CC=C)C2=C(C=CC=C2)/C1=N/C3=NC4=CC=CC=C4N3
Molecular Formula
C18H14N4O
Molecular Weight
302.33
References & Citations
[1]Shivani Jaiswal, et al. Lead optimization study on indoline-2,3-dione derivatives as potential fatty acid amide hydrolase inhibitors. J Biomol Struct Dyn. 2023, 41 19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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