AMPK-α1β1γ1 activator 1
AMPK-α1β1γ1 activator 1 (M1) is an acyl glucuronide metabolite of Indole-3-carboxylic Acid-based AMPK activator. AMPK-α1β1γ1 activator 1 can selectively activated human β1 isoforms with an EC50 value of 38.1nM. AMPK-α1β1γ1 activator 1 can direct binding with human AMPK α1β1γ1 isoform. AMPK-α1β1γ1 activator 1 can be used for the research of diabetic nephropathy[1].
Product Specifications
CAS Number
1943510-86-8
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ampk-α1β1γ1-activator-1.html
Solubility
10 mM in DMSO
Smiles
OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(C2=CNC3=CC(Cl)=C(C4=CC=C(C5(CCC5)O)C=C4)C=C23)=O)=O
Molecular Formula
C25H24ClNO9
Molecular Weight
517.91
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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