PI3Kδ-IN-18
Se15 is a selective inhibitor of PI3Kδ with an IC50 value less than 0.1nM. Se15 can be used in research on autoimmune[1].
Product Specifications
CAS Number
[3019965-38-6]
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pi3kδ-in-18.html
Solubility
10 mM in DMSO
Smiles
COC1=NC=C(C2=CC=C(N=CN=C3N[C@@H]4CN(C([C@@H](NC(OC(C)(C)C)=O)C[Se]C)=O)CC4)C3=N2)C=C1C#N
Molecular Formula
C27H32N8O4Se
Molecular Weight
611.55
References & Citations
[1]Li Gao, et al. Design, synthesis and bioactivity evaluation of selenium-containing PI3Kδ inhibitors. Bioorg Chem. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3Kδ
Curated Selection
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