ICMT-IN-49
ICMT-IN-49 (compound 2) is an inhibitor of ICMT (IC50=0.12 μM) [1].
Product Specifications
CAS Number
303728-92-9
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-49.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CO1)N(CC2=CC=CC=C2)CCC3(CCOC(C)(C)C3)C4=CC=CC=C4
Molecular Formula
C27H31NO3
Molecular Weight
417.54
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bsm-61242R-BF555-01 20 µL
STK3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details bsm-61242R-BF555-02 100 µL
STK3 Recombinant Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details 
NSL1008r 96 Tests
Rat 5-Hydroxyindoleacetic acid (5-HIAA) ELISA Kit
Sign In for Pricing
View Details