ICMT-IN-49
Product Specifications
UNSPSC Description
ICMT-IN-49 (compound 2) is an inhibitor of ICMT (IC50=0.12 μM)[1].
Target Antigen
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-49.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CO1)N(CC2=CC=CC=C2)CCC3(CCOC(C)(C)C3)C4=CC=CC=C4
Molecular Weight
417.54
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157117/ICMT-IN-49-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157117/
Clinical Information
No Development Reported
CAS Number
303728-92-9
Curated Selection
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