ICMT-IN-46
ICMT-IN-46 (compound 25) is an inhibitor of ICMT (IC50=0.556 μM) [1].
Product Specifications
CAS Number
1313602-71-9
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-46.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CC(CCNC2=CC=CC(C(C)(C)C)=C2)(C3=CC=CC=C3)CCO1
Molecular Formula
C25H35NO
Molecular Weight
365.55
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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