ICMT-IN-10
ICMT-IN-10 (compound 32) is an inhibitor of ICMT (IC50=0.184 μM) [1].
Product Specifications
CAS Number
1313602-78-6
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icmt-in-10.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)OC1=CC=C(C=C1)NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2
Molecular Formula
C22H26F3NO2
Molecular Weight
393.44
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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