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ICMT-IN-10

ICMT-IN-10 (compound 32) is an inhibitor of ICMT (IC50=0.184 μM) [1].

Product Specifications

CAS Number

1313602-78-6

UNSPSC

12352005

Target

ICMT

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/icmt-in-10.html

Solubility

10 mM in DMSO

Smiles

FC(F)(F)OC1=CC=C(C=C1)NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2

Molecular Formula

C22H26F3NO2

Molecular Weight

393.44

References & Citations

[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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