(R) -ICMT-IN-3
(R) -ICMT-IN-3 (compound ent 2-27) is an inhibitor of ICMT (IC50=0.01 μM) [1].
Product Specifications
UNSPSC
12352005
Target
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-icmt-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(OCC1)(C)C[C@@]1(C2=CC=CC=C2)CCNC3=CC=C(OC)C=C3
Molecular Formula
C22H29NO2
Molecular Weight
339.47
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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