(R)-ICMT-IN-3
Product Specifications
UNSPSC Description
(R)-ICMT-IN-3 (compound ent 2-27) is an inhibitor of ICMT (IC50=0.01 μM)[1].
Target Antigen
ICMT
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/r-icmt-in-3.html
Solubility
10 mM in DMSO
Smiles
CC(OCC1)(C)C[C@@]1(C2=CC=CC=C2)CCNC3=CC=C(OC)C=C3
Molecular Weight
339.47
References & Citations
[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT). J Med Chem. 2011 Jul 28;54(14):5031-47.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157092B/R-ICMT-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157092B/
Clinical Information
No Development Reported
Curated Selection
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