ICMT-IN-3

ICMT-IN-3 (compound 27) is an inhibitor of ICMT (IC50=0.015 μM) [1].

Product Specifications

CAS Number

[1313602-73-1]

UNSPSC

12352005

Target

ICMT

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/icmt-in-3.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=CC=C1

Molecular Formula

C22H29NO2

Molecular Weight

339.47

References & Citations

[1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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