AChE/MAO-B-IN-6

AChE/MAO-B-IN-6 (compound 3a) is a dual inhibitor of AChE and h-MAO-B with potential to inhibit Alzheimer's disease[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-mao-b-in-6.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=NN=C(S1)C23C[C@H](C4)C[C@@H](C3)C[C@H]4C2)CN5CCN(C6=NC=CC=N6)CC5

Molecular Formula

C22H29N7OS

Molecular Weight

439.58

References & Citations

[1]Al-Sharabi AA et al. Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer's disease. J Biomol Struct Dyn. 2023 Nov 1:1-19.