AChE/MAO-B-IN-6
AChE/MAO-B-IN-6 (compound 3a) is a dual inhibitor of AChE and h-MAO-B with potential to inhibit Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-mao-b-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=NN=C(S1)C23C[C@H](C4)C[C@@H](C3)C[C@H]4C2)CN5CCN(C6=NC=CC=N6)CC5
Molecular Formula
C22H29N7OS
Molecular Weight
439.58
References & Citations
[1]Al-Sharabi AA et al. Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer's disease. J Biomol Struct Dyn. 2023 Nov 1:1-19.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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