AChE/MAO-B-IN-4
Product Specifications
UNSPSC Description
AChE/MAO-B-IN-4 (compound 4a) is a selective dual AChE and MAO-B inhibitor. AChE/MAO-B-IN-4 shows no significant inhibition activity against BChE and h-MAO-A. AChE/MAO-B-IN-4 can be used for the Alzheimer’s disease (AD) research[1].
Target Antigen
Cholinesterase (ChE); Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-mao-b-in-4.html
Solubility
10 mM in DMSO
Smiles
CC(N1CCN(C2=NC=CC=N2)CC1)C(NC3=NN=C(S3)C45C[C@H](C6)C[C@@H](C5)C[C@H]6C4)=O
Molecular Weight
453.60
References & Citations
[1]Amal A Al-Sharabi, et al. Synthesis, characterization, molecular docking and molecular dynamics simulations of novel 2,5-disubstituted-1,3,4-thiadiazole derivatives as potential cholinesterase/monoamine oxidase dual inhibitors for Alzheimer's disease. J Biomol Struct Dyn. 2023 Nov 1:1-19.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157087/AChE-MAO-B-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157087/
Clinical Information
No Development Reported
Curated Selection
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