BX-2819
Product Specifications
UNSPSC Description
BX-2819 is a Hsp90 inhibitor with an IC50 value of 41 nM. BX-2819 inhibits the proliferation of cancer cells. BX-2819 can significantly inhibit the growth of NCI-N87 and HT-29 tumors in nude mice[1].
Target Antigen
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bx-2819.html
Solubility
10 mM in DMSO
Smiles
CCOC(NCC1=CC=C(C=C1)N2C(NN=C2C3=C(C=C(C(C(C)C)=C3)O)O)=S)=O
Molecular Weight
428.50
References & Citations
[1]Feldman RI, et al. Potent triazolothione inhibitor of heat-shock protein-90. Chem Biol Drug Des. 2009 Jul;74(1):43-50.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157085/BX-2819-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157085/
Clinical Information
No Development Reported
CAS Number
1184181-50-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1412248-01 0.02 mg (E-Coli)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details MBS1412248-02 0.02 mg (Yeast)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details 
MBS1412248-03 0.1 mg (E-Coli)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details MBS1412248-04 0.1 mg (Yeast)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details 
MBS1412248-05 0.02 mg (Baculovirus)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details MBS1412248-06 0.02 mg (Mammalian-Cell)
Recombinant Neurospora crassa Adenylate kinase 1 (adk-1)
Ask
View Details