MCMY020
MCMY020 is a covalent inhibitor of TEAD. mCMY020 effectively reduces YAP (Yes-associated protein) -driven transcription and selectively slows the proliferation of Hippo-deficient cancer cells. mCMY020 can be used in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcmy020.html
Solubility
10 mM in DMSO
Smiles
C=C(C(NC1=C2N=C(C=CN2N=C1)C3=CC=C(C=C3)C4CCCCC4)=O)F
Molecular Formula
C21H21FN4O
Molecular Weight
364.42
References & Citations
[1]Nutsch K, et al. A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. RSC Chem Biol. 2023 Aug 29;4 (11) :894-905.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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