ZHSI-1
ZHSI-1 is an EV71 (Enterovirus 71) inhibitor that inhibits EV71/CVA16 replication and virus-induced pyroptosis associated with viral pathogenesis. ZHSI-1 effectively prevents EV71 infection in neonatal and young mice in animal models. ZHSI-1 can be used to study viral infections such as hand, foot and mouth disease (HFMD) [1].
Product Specifications
CAS Number
[2925912-67-8]
UNSPSC
12352005
Target
Enterovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/zhsi-1.html
Solubility
10 mM in DMSO
Smiles
CC(NC1=NC(NC2=CC=C3C(C=CC=N3)=C2)=CC(C)=N1)C
Molecular Formula
C17H19N5
Molecular Weight
293.37
References & Citations
[1]Wang X, et al. Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16. J Cell Biol. 2023 Dec 4;222 (12) :e202303108.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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