SCO-L-Lysine

SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].

Product Specifications

CAS Number

[1309581-49-4]

UNSPSC

12352211

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sco-l-lysine.html

Solubility

10 mM in DMSO

Smiles

N[C@H](C(O)=O)CCCCNC(OC1C#CCCCCC1)=O

Molecular Formula

C15H24N2O4

Molecular Weight

296.36

References & Citations

[1]Anandi Kugele, et al. In situ EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code. Chem Commun (Camb) . 2021 Dec 3;57 (96) :12980-12983.