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MAGL-IN-10

MAGL-IN-10 is areversible monoacylglycerol lipase (MAGL) inhibitor with very good ADME properties and low in vivo toxicity.MAGL-IN-10 can be used for the research ofcancer, neurological disorders and inflammatory pathologies[1].

Product Specifications

CAS Number

3017151-83-3

UNSPSC

12352005

Target

MAGL

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/magl-in-10.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(O)=CC=C1F)N2CCC(CC3=CC=CC(SC4=NC=CC(C(F)(F)F)=C4)=C3)CC2

Molecular Formula

C25H22F4N2O2S

Molecular Weight

490.51

References & Citations

[1]Granchi C, et al. Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors. Eur J Med Chem. 2021 Jan 1;209:112857.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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