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Proteasome β2c/i-IN-1

Proteasome β2c/i-IN-1 (compound 37) is a subunit-selective human proteasome β2c and β2i inhibitor [1].

Product Specifications

CAS Number

2322333-75-3

UNSPSC

12352005

Target

Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/proteasome-β2c-i-in-1.html

Solubility

10 mM in DMSO

Smiles

COC(C=C1)=CC=C1C[C@H](NC([C@H](C)NC(CN2CCOCC2)=O)=O)C(N[C@@H](CCC3CCCCC3)C([C@]4(CO4)C)=O)=O

Molecular Formula

C32H48N4O7

Molecular Weight

600.75

References & Citations

[1]Xin BT, et al. Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits. J Med Chem. 2019 Feb 14;62 (3) :1626-1642.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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