UR-MB-355

UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities[1].

Product Specifications

UNSPSC

12352005

Target

GPR6

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ur-mb-355.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(OC(C)C)=C(C=C1)CNC2=CC(C3=CC=CC=C3OCCCCCCNC(C4=CC(C([O-])=O)=C(C=C4)C5=C6C=CC(N(C)C)=CC6=[O+]C7=C5C=CC(N(C)C)=C7)=O)=NC8=NC=NN28.O=C(O)C(F)(F)F

Molecular Formula

C54H54ClF3N8O8

Molecular Weight

1035.50

References & Citations

[1]Merlin Bresinsky, et al. Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3. J Med Chem. 2023 Nov 9;66 (21) :15025-15041.