JAK-IN-33
JAK-IN-33 (compound 3 (R) ) is a JAK inhibitor[1].
Product Specifications
CAS Number
3032404-49-9
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak-in-33.html
Solubility
10 mM in DMSO
Smiles
COC[C@H](OC(CC1=CC=C(N=C1)NC2=CC(NC3=CC=CC=C3OC)=C(C=N2)C(N)=O)=O)C
Molecular Formula
C24H27N5O5
Molecular Weight
465.50
References & Citations
[1]Thoma G, Decoret O, et al. Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood. J Med Chem. 2023;66 (21) :15042-15053.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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