Butobendine
Butobendine, a double ester of 2-aminobutanol and trimethoxybenzoic acid, is an antiarrhythmic agent[1]. Butobendine is a noncompetitive inhibitor of dopamine β-hydroxylase (DBH) [2].
Product Specifications
CAS Number
55769-65-8
UNSPSC
12352005
Target
Dopamine β-hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/butobendine.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C=C1OC)C(OC[C@H](CC)N(C)CCN(C)[C@@H](CC)COC(C2=CC(OC)=C(C(OC)=C2)OC)=O)=O)OC
Molecular Formula
C32H48N2O10
Molecular Weight
620.73
References & Citations
[1]M Grabowska, et al. Effect of butobendin on dopamine beta-hydroxylase in vitro. Pol J Pharmacol. 1996 Jan-Feb;48 (1) :39-45.|[2]Grabowska M, et al. Effect of butobendin on dopamine beta-hydroxylase in vitro. Pol J Pharmacol. 1996 Jan-Feb;48 (1) :39-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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