NOP agonist-1
Product Specifications
UNSPSC Description
NOP agonist-1(compound 4) is a nociceptin opioid receptor (NOP) partial agonist. NOP agonist-1attenuate parkinsonian disabilities in 6-OHDA hemilesioned rats[1].
Target Antigen
Opioid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/nop-agonist-1.html
Solubility
10 mM in DMSO
Smiles
CC([C@H]1CC[C@H](CC1)N2CCC(CC2)N3C4=CC=CC=C4CC3)C
Molecular Weight
326.52
References & Citations
[1]Kamakolanu UG, et al. Discovery and Structure-Activity Relationships of Nociceptin Receptor Partial Agonists That Afford Symptom Ablation in Parkinson's Disease Models. J Med Chem. 2020;63(5):2688-2704
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156972/NOP-agonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156972/
Clinical Information
No Development Reported
CAS Number
2099681-43-1
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