Topoisomerase I inhibitor 11
Selected Variant
HY-156969
Size: 1 Each
Topoisomerase I inhibitor 11 is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 11 can bind to BTK[1].
Product Specifications
CAS Number
2922723-28-0
UNSPSC
12352005
Target
Btk; Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-11.html
Solubility
10 mM in DMSO
Smiles
NC1=C2C(N([C@H](CCC3)CN3C(C(CN(C(C=C4)=O)C=C4CNC(N5N=C6)=CC(N(CCCC7)[C@@H]7CCO)=NC5=C6CC)=C)=O)N=C2C(C=C8)=CC=C8OC9=CC=CC=C9)=NC=N1
Molecular Formula
C47H52N12O4
Molecular Weight
848.99
References & Citations
[1]Gerritz Samuel W, et al. Preparation of heterobifunctional compounds and their use in treating disease. World Intellectual Property Organization, WO2023059582 A1 2023-04-13
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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