BAY-771
BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux) . BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism[1].
Product Specifications
CAS Number
[2771756-82-0]
UNSPSC
12352005
Target
Fluorescent Dye
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bay-771.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(F)(F)F)=CC(N1C2=CC(OC3=C(C)C=CC=C3)=CC4=C2C=CC=C4)=O
Molecular Formula
C22H15F3N2O3
Molecular Weight
412.36
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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