P53 Activator 8
P53 Activator 8 (compound 5) is a p53 activator. p53 Activator 8 has potent anti-proliferative activity against MCF7 breast cancer cell lines with an IC50 value of 0.5 μM[1][2].
Product Specifications
CAS Number
1426937-93-0
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-activator-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(CO)C(CO)=C2N1[C@H](C3=CC=CC=C3)SC2
Molecular Formula
C15H17NO2S
Molecular Weight
275.37
References & Citations
[1]ATAÍDE SARAIVA, et al. WO2019243906. 2019.|[2]Maria I L Soares, et al. Chiral 6,7-bis (hydroxymethyl) -1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties. Eur J Med Chem. 2013.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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