3-OH-Kynurenamine
3-OH-Kynurenamine is a lateral metabolite in Tryptophan (HY-N0623) metabolism. 3-OH-Kynurenamine induces a concentration-dependent AhR activation, around 6.5 times higher than L-kynurenine (HY-104026) . 3-OH-Kynurenamine confers immunosuppressive properties on dendritic cells (DCs) . 3-OH-Kynurenamine can be used for psoriasis research[1].
Product Specifications
CAS Number
[99362-47-7]
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3-oh-kynurenamine.html
Solubility
10 mM in DMSO
Smiles
O=C(CCN)C1=C(N)C(O)=CC=C1
Molecular Formula
C9H12N2O2
Molecular Weight
180.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Laura SANTAMBROGIO. Immunoregulatory role of 3-oh-kynurenamine and uses thereof. Patent, WO2019178013A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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