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Antiproliferative agent-39

Product Specifications

UNSPSC Description

Antiproliferative agent-39 (Compound 12) inhibits proliferation of A549, SNU-638, Col2, HT1080, MCF-7 with IC50s of 11, 25, 14, 11, 6.3 μM respectively[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-39.html

Solubility

10 mM in DMSO

Smiles

O=C1NC2=C(/C1=C3NC4=C(C/3=N\O)C=CC=C4)C=C(NC(CC(C)(C)C)=O)C=C2

Molecular Weight

390.44

References & Citations

[1]Moon MJ, et al. Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities. Bioorg Med Chem. 2006 Jan 1;14(1):237-46.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156878/Antiproliferative-agent-39-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156878/

Clinical Information

No Development Reported

CAS Number

9007-83-4

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