TTNPB (GMP)

TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist[1][2].

Product Specifications

CAS Number

[71441-28-6]

Product Name Alternative

Ro 13-7410 (GMP) ; Arotinoid acid (GMP) ; AGN191183 (GMP)

UNSPSC

12352005

Hazard Statement

H315-H319-H335-H360

Target

RAR/RXR

Type

GMP Small Molecules

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ttnpb-gmp.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1

Molecular Formula

C24H28O2

Molecular Weight

348.48

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410) : binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142 (2) :319-27.|[2]Manabu Kawata, et al. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds. Stem Cell Reports. 2019 Sep 10;13 (3) :530-544.