PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1)
PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA) : glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity[1].
Product Specifications
UNSPSC
12352211
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plga-peg-plga-1500-1500-1500-la-ga-15-1.html
Solubility
10 mM in DMSO
Smiles
[H]OC(C)C(OCC(OCCOC(C(C)OC(CO[H])=O)=O)=O)=O.[x].[y].[m].[x].[y].[n].[m]
Molecular Weight
Average Mn (1500-1500-1500)
References & Citations
[1]Xiufen Chen, et al. PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment. J Colloid Interface Sci. 2017 Mar 15:490:542-552.|[2]Yuan Gao, et al. A thermo-sensitive PLGA-PEG-PLGA hydrogel for sustained release of docetaxel. J Drug Target. 2011 Aug;19 (7) :516-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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