Cholesterol 24-hydroxylase-IN-2
Product Specifications
UNSPSC Description
Cholesterol 24-hydroxylase-IN-2 is an inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), with the IC50 of 5.4 nM. Cholesterol 24-hydroxylase-IN-2 can be used in imaging of cholesterol 24-hydroxylase in mammals[1].
Target Antigen
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
others
Assay Protocol
https://www.medchemexpress.com/cholesterol-24-hydroxylase-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCN(CC1)C2=C(C3=CC=C(F)C=C3)N=CN=C2)N(C4CC4)C
Molecular Weight
354.42
References & Citations
[1]Koike Tatsuki, et al. Preparation of arylpiperidines and arylpiperazines as radiolabeled compounds for use in imaging of cholesterol 24-hydroxylase. World Intellectual Property Organization, WO2015190613 A1 2015-12-17
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156799/Cholesterol-24-hydroxylase-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156799/
Clinical Information
No Development Reported
CAS Number
1613481-52-9
Curated Selection
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