PROTAC CDK9/CycT1 Degrader-2
PROTAC CDK9/CycT1 Degrader-2 is a inhibitor of CDK9, with the IC50 of 45 nM[1].
Product Specifications
CAS Number
3020773-91-2
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-cdk9-cyct1-degrader-2.html
Solubility
10 mM in DMSO
Smiles
O=C1OC2=CC(OCCCN3CCC(CC3)C(NC4=NC=C(S4)SCC5=NC=C(O5)C(C)(C)C)=O)=CC(O)=C2C(C)=C1
Molecular Formula
C30H36N4O6S2
Molecular Weight
612.76
References & Citations
[1]Harald Gollnick, et al. Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs. Expert Opin Pharmacother. 2008 Oct;9 (15) :2699-706.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
Frequently Asked Questions
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