FGFR3-IN-6

FGFR3-IN-6 is a potent and selective FGFR3 inhibitor with IC50 value less than 350 nM. FGFR3-IN-6 can be used in research of cancer[1].

Product Specifications

CAS Number

[2833703-72-1]

UNSPSC

12352005

Target

FGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fgfr3-in-6.html

Solubility

10 mM in DMSO

Smiles

OC[C@H](C1=CC=C(C=N1)F)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(C#N)C=N5

Molecular Formula

C25H23FN8O2

Molecular Weight

486.50

References & Citations

[1]Abraham Adedoyin David, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. World Intellectual Property Organization, WO2022187443 A1 2022-09-09

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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