FGFR3-IN-6
FGFR3-IN-6 is a potent and selective FGFR3 inhibitor with IC50 value less than 350 nM. FGFR3-IN-6 can be used in research of cancer[1].
Product Specifications
CAS Number
[2833703-72-1]
UNSPSC
12352005
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fgfr3-in-6.html
Solubility
10 mM in DMSO
Smiles
OC[C@H](C1=CC=C(C=N1)F)OC2=CC(C3=C(N(C4CCN(CC4)C#N)N=C3)C)=CN5C2=C(C#N)C=N5
Molecular Formula
C25H23FN8O2
Molecular Weight
486.50
References & Citations
[1]Abraham Adedoyin David, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. World Intellectual Property Organization, WO2022187443 A1 2022-09-09
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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