METTL3-IN-5
Product Specifications
UNSPSC Description
METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research[1].
Target Antigen
METTL3
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mettl3-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C(NCC2=CC3=C(C=C(CNCC45CC(C4)(C5)F)N3)S2)=O)N=C6C=CC=CN16
Molecular Weight
451.52
References & Citations
[1]Zhong Chen, et al. Mettl3 inhibitor and composition, and application of same in medicine. WO2023151697 A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156759/METTL3-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156759/
Clinical Information
No Development Reported
CAS Number
2965311-25-3
Curated Selection
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