3β-Hydroxy-lup-20 (29) -en-16-one
3β-Hydroxy-lup-20 (29) -en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM) [1].
Product Specifications
CAS Number
[65043-60-9]
UNSPSC
12352211
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3β-hydroxy-lup-20-29-en-16-one.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)([H])[C@]5([H])[C@@](C(C3)=O)(CC[C@H]5C(C)=C)C)C
Molecular Formula
C30H48O2
Molecular Weight
440.70
References & Citations
[1]Castro MJ, et al. Oxidation at C-16 enhances butyrylcholinesterase inhibition in lupane triterpenoids. Bioorg Chem. 2018 Sep;79:301-309.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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