Pomalidomide-amino-PEG4-C4-Cl
Pomalidomide-amino-PEG4-C4-Cl (Intermediate 4d) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide-amino-PEG4-C4-Cl can be used in the synthesis of PROTAC[1].
Product Specifications
CAS Number
[2924835-36-7]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-amino-peg4-c4-cl.html
Solubility
10 mM in DMSO
Smiles
O=C(COCCOCCOCCOCCCCCCCl)NC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
Molecular Formula
C27H36ClN3O9
Molecular Weight
582.04
References & Citations
[1]Yuanying Fang, et al. A PROTAC Compound for Targeted Degradation of PTP1b and Its Preparation Method and Application. CN115677815A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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