TLR7/8 agonist 4 hydroxy-PEG6-acid

TLR7/8 agonist 4 hydroxy-PEG6-acid is a drug-linker conjugates for ADC. TLR7/8 agonist 4 hydroxy-PEG6-acid consists of TLR7/8 agonist 4 (HY-139017) and a non-cleavable linker Hydroxy-PEG6-acid (HY-133050), and can be used for synthesis of ADCs[1].

Product Specifications

CAS Number

[2388520-23-6]

UNSPSC

12352005

Target

Drug-Linker Conjugates for ADC

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tlr7-8-agonist-4-hydroxy-peg6-acid.html

Solubility

10 mM in DMSO

Smiles

O=C(CCOCCOCCOCCOCCOCCOCCN1CCN(CC1)C2=CC3=C(N=C(C4=C3NC(CCCC)=N4)N)C=C2)O

Molecular Formula

C33H52N6O8

Molecular Weight

660.80

References & Citations

[1]Shelley Erin ACKERMAN, et al. Macromolecule-supported tlr agonists. Patent. WO2020190762A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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