Tibremciclib
Tibremciclib is a CDK4 inhibitor with antineoplastic activity[1].
Product Specifications
CAS Number
[2397678-18-9]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tibremciclib.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CCC1
Molecular Formula
C28H32F2N8
Molecular Weight
518.60
References & Citations
[1]Wang Yiqian, et al. Crystal form of compound useful as CDK4/6 inhibitors for the treatment of cancer. World Intellectual Property Organization, WO2019242719 A1. 2019-12-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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