Ionizable lipid-1 (hydrochloride)
Ionizable lipid-1 (compound II-10) is an ionizable lipid (pKa=6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure[1].
Product Specifications
UNSPSC
12352200
Target
Liposome
Type
Biochemical Assay Reagents
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ionizable-lipid-1-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
[H]Cl.O=C(CCCCCCCCC(CCCCCCCCC(OC(CCCCCC)CCCCCC)=O)N(CCCN(C)C)C(CCCCCCC)=O)OC(CCCCCC)CCCCCC
Molecular Formula
C58H115ClN2O5
Molecular Weight
956.00
References & Citations
[1]Thomas D Madden, et al. Lamellar lipid nanoparticles. Patent WO2019089828A1.|[2]Ramaswamy S, et al., Systemic delivery of factor IX messenger RNA for protein replacement therapy. Proc Natl Acad Sci U S A. 2017 Mar 7;114 (10) :E1941-E1950.
Shipping Conditions
Room temperature
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Curated Selection
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