Anticancer agent 144
Anticancer agent 144 (compound 444) is a dual PTPN2/PTP1B inhibitor with IC50 values [1].
Product Specifications
CAS Number
[2948340-59-6]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-144.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(C(F)(C1=C(Br)C2=C(C(OCC3=CC=C(S(=O)(C)=O)C=C3)=CC(C4=NN=CN4)=C2)S1)F)O
Molecular Formula
C19H15BrF2N3O6PS2
Molecular Weight
594.34
References & Citations
[1]David A CANDITO, et al. Substituted benzothiophene derivatives and methods of use thereof. Patent WO2023121939A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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