Anticancer agent 144
Anticancer agent 144 (compound 444) is a dual PTPN2/PTP1B inhibitor with IC50 values [1].
Product Specifications
CAS Number
[2948340-59-6]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-144.html
Solubility
10 mM in DMSO
Smiles
O=P(O)(C(F)(C1=C(Br)C2=C(C(OCC3=CC=C(S(=O)(C)=O)C=C3)=CC(C4=NN=CN4)=C2)S1)F)O
Molecular Formula
C19H15BrF2N3O6PS2
Molecular Weight
594.34
References & Citations
[1]David A CANDITO, et al. Substituted benzothiophene derivatives and methods of use thereof. Patent WO2023121939A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6477732-01 0.1 mL
GFR alpha1, IN (GDNFRa, Glial Cell-derived Neurotrophic Factor Receptor a1, RETL1, Ret ligand 1, TGFb-related Neurotrophic Factor Receptor 1, TrnR1, Glycosylphosphadidylinositol linked Protein) (MaxLight 650)
Ask
View Details 
MBS6477732-02 5x 0.1 mL
GFR alpha1, IN (GDNFRa, Glial Cell-derived Neurotrophic Factor Receptor a1, RETL1, Ret ligand 1, TGFb-related Neurotrophic Factor Receptor 1, TrnR1, Glycosylphosphadidylinositol linked Protein) (MaxLight 650)
Ask
View Details 
MBS7198681 Inquire
Rabbit anti-Ashbya gossypii (strain 10895/CBS 109.51/FGSC 9923/NRRL Y-1056)(Yeast)(Eremothecium gossypii) GEP5 Polyclonal Antibody
Ask
View Details GTR15264502 1 Vial
Lentiviral mouse Vmn2r82 shRNA (UAS) - Lentiviral mouse Vmn2r82 shRNA (UAS, GFP) plasmid
Ask
View Details