Bocodepsin (hydrochloride)

Bocodepsin hydrochloride (OKI-179) is an orally active and selective HDAC inhibitor, with antitumor activity. Bocodepsin hydrochloride can be used for suppression on solid tumor and hematologic malignancies[1].

Product Specifications

CAS Number

[1834513-66-4]

Product Name Alternative

OKI-179 (hydrochloride)

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bocodepsin-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=CSC(CNC(C[C@H](OC([C@@H](NC(C(C)(N1)C)=O)C(C)C)=O)/C=C/CCSC([C@@H](N)C(C)C)=O)=O)=N2.[H]Cl

Molecular Formula

C26H40ClN5O6S2

Molecular Weight

618.21

References & Citations

[1]Diamond JR, et al. Preclinical Development of the Class-I-Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors. Mol Cancer Ther. 2022 Mar 1;21 (3) :397-406.