PROTAC BRD4 Degrader-21
PROTAC BRD4 Degrader-21 (Comp 74) is a PROTAC degrader of BRD4. PROTAC BRD4 Degrader-21 displays significant tumor growth inhibition in tumor -bearing xenograft models in mice and can be used for anticancer research[1].
Product Specifications
CAS Number
2503036-46-0
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-degrader-21.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N4CCC(CC4)CN5CCN(CC5)CC6=CC=C(N7C(C8=CC(C(C)C)=C(C=C8O)O)=NNC7=O)C=C6)=O)C9=NN=C(C)N29.Cl
Molecular Formula
C47H54Cl2N10O4S
Molecular Weight
925.97
References & Citations
[1]Weiwen Ying, et.al. Methods and compositions for targeted protein degradation
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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