Raf inhibitor 3
Raf inhibitor 3 (Example 30) is a Raf inhibitor. Raf inhibitor 3 inhibits B-Raf and C-Raf with IC50 values less than 15 nM. Raf inhibitor 3 can be used for research of cancers[1].
Product Specifications
CAS Number
[1662682-11-2]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/raf-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
O=S(NC1=C(F)C(C2=NN(C(C)C)N=C2C3=CNN=C3)=CC=C1)(C4=CN(C)N=C4)=O
Molecular Formula
C18H19FN8O2S
Molecular Weight
430.46
References & Citations
[1]Angus Morrison, et al. Preparation of triazole derivatives as inhibitors of Raf kinases. Patent. GB2517988.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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