Raf inhibitor 3

Raf inhibitor 3 (Example 30) is a Raf inhibitor. Raf inhibitor 3 inhibits B-Raf and C-Raf with IC50 values less than 15 nM. Raf inhibitor 3 can be used for research of cancers[1].

Product Specifications

CAS Number

[1662682-11-2]

UNSPSC

12352005

Target

Raf

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/raf-inhibitor-3.html

Solubility

10 mM in DMSO

Smiles

O=S(NC1=C(F)C(C2=NN(C(C)C)N=C2C3=CNN=C3)=CC=C1)(C4=CN(C)N=C4)=O

Molecular Formula

C18H19FN8O2S

Molecular Weight

430.46

References & Citations

[1]Angus Morrison, et al. Preparation of triazole derivatives as inhibitors of Raf kinases. Patent. GB2517988.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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