Porcn-IN-2
Porcn-IN-2 (Example 107) is a Wnt inhibitor, with an IC50 value of 0.05 nM. Porcn-IN-2 can be used for research of cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia, etc[1].
Product Specifications
CAS Number
1900754-65-5
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/porcn-in-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C2=CC=C(NC(CN3C=NC(C4=CC(C(F)(F)F)=NC=C4)=C3C)=O)N=C2)C=C1
Molecular Formula
C24H17F3N6O
Molecular Weight
462.43
References & Citations
[1]Inder Bhamra, et al. N-pyridinyl acetamide derivatives as inhibitors of the wnt signalling pathway. Patent. WO2016055786.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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