Porcn-IN-2
Porcn-IN-2 (Example 107) is a Wnt inhibitor, with an IC50 value of 0.05 nM. Porcn-IN-2 can be used for research of cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia, etc[1].
Product Specifications
CAS Number
1900754-65-5
UNSPSC
12352005
Target
Wnt
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/porcn-in-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=C(C2=CC=C(NC(CN3C=NC(C4=CC(C(F)(F)F)=NC=C4)=C3C)=O)N=C2)C=C1
Molecular Formula
C24H17F3N6O
Molecular Weight
462.43
References & Citations
[1]Inder Bhamra, et al. N-pyridinyl acetamide derivatives as inhibitors of the wnt signalling pathway. Patent. WO2016055786.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90]](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea820aa/imageurl/ha721381.webp)
HA721381 100 µL
PON1 Recombinant Rabbit Monoclonal Antibody [JE30-90]
Sign In for Pricing
View Details ![Biotin Conjugated Mouse IL-6 Recombinant Rabbit Monoclonal Antibody [PS01-83] - BSA and Azide free (Detector)](https://cdn.genprice.uk/products/992/68dd1c8d061270361ea8206e/imageurl/ha721602.webp)
HA721602 100 µL
Biotin Conjugated Mouse IL-6 Recombinant Rabbit Monoclonal Antibody [PS01-83] - BSA and Azide free (Detector)
Sign In for Pricing
View Details 
BNC471219-500 1x 500 µL
Cytokeratin 8 (B22.1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
TP322241M 100 µg
Adenylate kinase 5 (AK5) (NM_174858) Human Recombinant Protein
Sign In for Pricing
View Details 
AN301007L-01 50 µL
Recombinant Pyruvate Dehydrogenase E1 α Monoclonal Antibody
Sign In for Pricing
View Details